Category 182
Broad WGS pilot - Whole genome sequences - Genomics

Description

During Q1/2018, UK Biobank made available a small number of samples to run 'proof-of-concept' whole genome sequencing to allow service providers be confident that their chosen technology platform would meet UK Biobank's quality requirements. As part of this, 48 samples (with an additional two blind spike duplicates) were provided to the Broad Institute (Harvard/MIT). This category contains the results of this exercise.

The samples provided contained 100 microL total sample volume normalised to 20 nanograms/microL (2 nano-g total yield) and quantified via UV/VIS spectroscopy using Trinean DropSense 96 platform. The Broad Institute sequenced these using an Illumina NovaSeq platform.