| Title: | Hidden dangers: does multisensory impairments accompanying visual impairment increase dementia risk |
| Journal: | Journal of Psychiatric Research |
| Published: | 23 Apr 2024 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/38678684/ |
| DOI: | https://doi.org/10.1016/j.jpsychires.2024.04.041 |
Publication 9847
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Abstract
BACKGROUND: Growing evidence suggests that sensory impairment, particularly in the form of visual impairment, may contribute to the development of dementia. However, it remains unclear whether experiencing concurrent visual impairment in combination with other types of multisensory impairments may further increase this risk.</p>
METHODS: The study used data from the UK Biobank cohort study, which recruited 500,000 adults. With meticulous screening procedures in place, individuals with visual impairment, hearing impairment, and oral health issues were identified for further follow-up evaluations. A multivariable regression analysis was conducted to investigate the relationship between multisensory impairments concurrent with visual impairment and cognitive function. Cox proportional hazard models were used to estimate hazard ratios and 95% confidence intervals to evaluate the association between multisensory impairments concurrent with visual impairment and dementia risk.</p>
RESULTS: Subjects experiencing multisensory impairments concurrent with visual impairment demonstrated a negative association with cognitive function. Notably, individuals who have both vision and hearing impairments had a significantly higher risk of developing dementia (HR 1.28, 95% CI [1.01-1.63]). Additionally, individuals who experience vision impairment and oral health issues simultaneously were also at higher risk for dementia (HR 1.61, 95% CI [1.32-1.97]). Furthermore, the risk of dementia among individuals with vision impairment, hearing impairment, and oral health issues further escalated to an even higher level (HR 1.63, 95% CI [1.19-2.24]).</p>
CONCLUSIONS: The correlation between the presence of multisensory impairments concurrent with visual impairment and cognitive decline is highly significant. Those with multisensory impairments concurrent with visual impairment are at a significantly increased risk of developing dementia.</p>
8 Authors
- Xiaojuan Shi
- Yueping Wu
- Huihui Wang
- Xiaoxue He
- Xue Zhang
- Lining Pu
- Degong Pan
- Jiangping Li
1 Application
| Application ID | Title |
|---|---|
| 98124 | Understanding the patterns of multimorbidity, and the role of environmental, lifestyle-related, psychological and genetic factors |
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