| Title: | Diurnal Preference and Grey Matter Volume in a Large Population of Older Adults: Data from the UK Biobank |
| Journal: | Journal of Circadian Rhythms |
| Published: | 8 May 2020 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/32405316/ |
| DOI: | https://doi.org/10.5334/jcr.193 |
| URL: | http://www.jcircadianrhythms.com/articles/10.5334/jcr.193/galley/330/download/ |
Publication 4715
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Abstract
Eveningness (a diurnal preference for evening time) is associated with a number of negative health outcomes and risk and prevalence for psychiatric disorder. Our understanding of the anatomical substrates of diurnal preference, however, is limited. The current study used Voxel-Based Morphometry to compare grey matter volume in a large sample (N = 3730) of healthy adults determined by questionnaire to be either definite morning-type or definite evening-type. Eveningness was associated with increased grey matter volume in precuneus, brain regions implicated in risk and reward processing (bilateral nucleus accumbens, caudate, putamen and thalamus) and orbitofrontal cortex. These results indicate an anatomical-basis for diurnal preference which may underlie reported differences in behaviour and brain function observed in these individuals.</p>
1 Author
- Ray Norbury
Enabling scientific discoveries that improve human health