| Title: | Wearable-device-measured physical activity and future health risk |
| Journal: | Nature Medicine |
| Published: | 17 Aug 2020 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/32807930/ |
| DOI: | https://doi.org/10.1038/s41591-020-1012-3 |
| URL: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116559 |
Publication 6001
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Abstract
Use of wearable devices that monitor physical activity is projected to increase more than fivefold per half-decade1. We investigated how device-based physical activity energy expenditure (PAEE) and different intensity profiles were associated with all-cause mortality. We used a network harmonization approach to map dominant-wrist acceleration to PAEE in 96,476 UK Biobank participants (mean age 62 years, 56% female). We also calculated the fraction of PAEE accumulated from moderate-to-vigorous-intensity physical activity (MVPA). Over the median 3.1-year follow-up period (302,526 person-years), 732 deaths were recorded. Higher PAEE was associated with a lower hazard of all-cause mortality for a constant fraction of MVPA (for example, 21% (95% confidence interval 4-35%) lower hazard for 20 versus 15 kJ kg−1 d−1 PAEE with 10% from MVPA). Similarly, a higher MVPA fraction was associated with a lower hazard when PAEE remained constant (for example, 30% (8-47%) lower hazard when 20% versus 10% of a fixed 15 kJ kg−1 d−1 PAEE volume was from MVPA). Our results show that higher volumes of PAEE are associated with reduced mortality rates, and achieving the same volume through higher-intensity activity is associated with greater reductions than through lower-intensity activity. The linkage of device-measured activity to energy expenditure creates a framework for using wearables for personalized prevention.</p>
9 Authors
- Tessa Strain
- Katrien Wijndaele
- Paddy C. Dempsey
- Stephen J. Sharp
- Matthew Pearce
- Justin Jeon
- Tim Lindsay
- Nick Wareham
- Søren Brage
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