| Title: | The Impact of Early Childhood Threats and Adoption Experiences on Brain Structures and Functions Involved in Threat Processing: Exploring the Influence of Low-grade Inflammation and Telomere Length |
| Lead Institution: | Guangzhou University |
| Principal investigator: |
Application 138512
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About
What We're Doing: We're exploring how tough experiences in early childhood, like facing threats or getting adopted, might change the way our brains are built and how they work. We're especially interested in two things that our bodies can show us: inflammation (a bit like when a cut becomes red and swollen) and telomere length (tiny parts at the end of our DNA that can tell us about our health). Why We're Doing It: We believe that by understanding these changes in the brain and what our bodies show, we can get clues about how early tough times might affect our health as we grow up. This knowledge can help us find ways to support those who've had challenging starts in life. How Long It'll Take: Our project will run for two or three years. Why It Matters: Our health isn't just about what we eat or how often we exercise. It's also about the experiences we've had, especially when we were kids. By understanding these early influences, we can make better choices for public health. This means healthier communities and support for those who need it most. In simple terms: We're trying to figure out how early life challenges might change our brains and health. This will help communities support those affected and lead to healthier futures for everyone.1 Publication
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 20317 | Stage-specific effects of early-life tobacco exposure on mental health, inflammation, and brain structure-function coupling | Yanqing Zhang (+3) | 2026 | Translational Psychiatry |
Enabling scientific discoveries that improve human health