| Title: | Combining imaging data with genomic and phenotypic data to improve the whole-course management of human noncommunicable diseases |
| Lead Institution: | Southeast University |
| Principal investigator: |
Application 151193
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About
Noncommunicable diseases (NCDs), mainly including cardiovascular disease, tumours, chronic respiratory disease and diabetes, are the biggest health problem worldwide. They result from a combination of genetic, physiological, environmental and behavioural factors. Thus, precise identification of risk factors and a deep understanding of pathogenesis are necessary in the prevention, detection, and treatment of NCDs. Current tools that aim to improve the management of NCDs are based on simple measurements and markers and do not work well. In the following three years, we intend to identify the risk factors of the development and the progression of NCDs, explore the imaging value in the interpretation, detection and treatment of NCDs, and combine multi-dimensional variables (including genetic, phenotypic, and imaging data) to promote the diagnosis and treatment of NCDs. As radiologists, we will also sufficiently investigate the essential correlations between imaging data and with occurrence and progression of NCDs, especially based on the genetics and corresponding pathophysiological mechanisms. Our work will provide new insights into public health research for disease prevention, diagnosis and treatment of NCDs, and should assist medical practitioners and society in general by improving healthcare decision-making.1 Publication
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 16880 | Association between metabolic score for visceral fat and adverse outcomes in chronic obstructive pulmonary disease | Kai Ma (+6) | 2026 | BMJ Open Respiratory Research |
Enabling scientific discoveries that improve human health