| Title: | Further understanding of cardiovascular and metabolic disorders using large cohort and multimodal data in the UK Biobank |
| Lead Institution: | Fuwai Hospital Chinese Academy of Medical Sciences |
| Principal investigator: |
Application 217390
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About
This project aims to identify all potential risk factors including lifestyles, serum biomarkers, genetic data, electrograms data, imaging data, and create a prediction system for cardiovascular and metabolic disorders. To our best knowledge, most current studies only focusing on single modality data. Therefore, we are engaged to develop a multivariate scoring system to improve the predictive value for cardiovascular and metabolic disorders. The current project is expected to last three to five years, and wish that it will be the most useful and precise scoring system to evaluate cardiovascular and metabolic disorders. The establishment of the predicting system can help identify the high-risk population. The earlier detection and control of the cardiovascular and metabolic disorders, the better the prognosis is.3 Publications
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 19119 | Associations between triglyceride-glucose-related indices and all-cause and cardiovascular mortality among individuals with atrial fibrillation and metabolic syndrome: a cohort study of the UK biobank | Lei Ding (+8) | 2025 | Cardiovascular Diabetology |
| 21038 | Effect of clonal hematopoiesis of indeterminate potential on long-term survival in patients with arrhythmias | Lei Ding (+11) | 2026 | Journal of Translational Medicine |
| 17442 | Histidine and the risk of incident atrial fibrillation and post-ablation recurrence: evidence from two prospective cohorts | Hongxuan Xu (+5) | 2026 |
Enabling scientific discoveries that improve human health