| Title: | Investigating phenotypic and genotypic characteristics that influence degenerative bone disease |
| Lead Institution: | Tongji Hospital |
| Principal investigator: | Dr Kehan Song |
Application 81888
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About
Degenerative bone diseases represent a major threat to the health and well-being of the population, particularly those with advanced age. Osteoporosis and osteoarthritis are the typical examples of degenerative bone disease. However, the influencing factor of degenerative bone disease remains to be comprehensively explored. This project aims to investigate the potential characteristics [including habitual characteristics (diet, physical activity, smoking, etc.), clinical characteristics (physical parameters, disease state, laborotary examinations, medication use, etc.), and genetic characteristics] that influence degenerative bone disease (characterised by osteoporosis and osteoarthritis). The estimated project duration is 3 years. The project will identify populations at higher risk for degenerative bone disease, which is essential for formulating targeted strategies for controlling the disease and in the public health interest.2 Publications
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 8939 | Higher Risk of Rheumatoid Arthritis in Patients With Chronic Rhinosinusitis: Prospective Association in the U.K. Biobank and Genetic Evidence by Mendelian Randomization Analysis | Yimin Dong (+3) | 2024 | American Journal of Rhinology and Allergy |
| 9078 | Higher risk of osteoporosis in adult-onset asthma than childhood-onset asthma: from genetic and prospective evidence | Weizhong Ding (+7) | 2023 | Osteoporosis International |
Enabling scientific discoveries that improve human health