| Title: | Association of healthy sleep pattern with risk of recurrent cardiovascular events among patients with coronary heart disease |
| Journal: | European Heart Journal - Quality of Care and Clinical Outcomes |
| Published: | 19 Jul 2023 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/37468441/ |
| DOI: | https://doi.org/10.1093/ehjqcco/qcad043 |
Publication 10522
WARNING: the interactive features of this website use CSS3, which your browser does not support. To use the full features of this website, please update your browser.
Abstract
AIMS: To examine the association of a healthy sleep pattern with the risk of recurrent cardiovascular events among patients with coronary heart disease (CHD).</p>
METHODS AND RESULTS: This prospective cohort study included 21 193 individuals with CHD from the UK Biobank. A healthy sleep score was generated based on a combination of chronotype, sleep duration, insomnia, and excessive daytime sleepiness. Cox proportional hazards regression models were applied to estimate the associations between healthy sleep score and recurrent cardiovascular events. During a median of 11.1 years of follow up, we documented 3771 recurrent cardiovascular events, including 1634 heart failure cases and 704 stroke cases. After multivariable adjustment, including lifestyle factors, medical history, and CHD duration, sleep 7-8 h/day, never/rarely insomnia, and no frequent daytime sleepiness were each significantly associated with a 12-22% lower risk of heart failure. In addition, compared with participants who had a healthy sleep score of 0-1, the multivariable-adjusted HR (95% CI) for participants with a healthy sleep score of 4 was 0.86 (0.75, 0.99) for recurrent cardiovascular events, 0.71 (0.57, 0.89) for heart failure, and 0.72 (0.51, 1.03) for stroke.</p>
CONCLUSIONS: Adherence to a healthy sleep pattern was significantly associated with a lower risk of recurrent cardiovascular events among patients with CHD, especially for heart failure. These findings indicate that healthy sleep behaviours could be beneficial in the prevention of cardiovascular event recurrence.</p>
15 Authors
- Sen Liu
- Yuexuan Wang
- Qi Lu
- Xue Chen
- Tingting Geng
- Rui Li
- Yulei Deng
- Lin Li
- Xiaoyu Lin
- Yunjing Ou
- Qingying Tian
- Guanglin Cui
- Kun Yang
- An Pan
- Gang Liu
1 Application
| Application ID | Title |
|---|---|
| 68307 | Environmental and genetic determinants of morbidity and mortality among adults with cardiometabolic disorders |
Enabling scientific discoveries that improve human health