| Title: | Adherence to a healthy sleep pattern and incidence of cardiometabolic multimorbidity among hypertensive patients: a prospective study of UK Biobank |
| Journal: | Sleep |
| Published: | 23 Jun 2022 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/35738866/ |
| DOI: | https://doi.org/10.1093/sleep/zsac141 |
| URL: | https://academic.oup.com/sleep/advance-article-pdf/doi/10.1093/sleep/zsac141/45014958/zsac141.pdf |
| Citations: | 11 (10 in last 2 years) as of 8 Aug 2024 |
Publication 7103
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Abstract
STUDY OBJECTIVES: To investigate whether a healthy sleep pattern would reduce the risk of cardiometabolic multimorbidity (CMM) among hypertensives.</p>
METHODS: This is a prospective cohort analysis from the UK Biobank. A total of 69 524 hypertensives without a history of diabetes mellitus, coronary heart disease, or stroke at baseline were enrolled. Five dimensions of healthy sleep at baseline including early chronotype, sleep 7-8 h/d, free of insomnia, no snoring, and no frequent excessive daytime sleepiness were used to generate a healthy sleep score ranging from 0 to 5 (one point was given for each dimension of healthy sleep). A higher score indicated a healthier sleep pattern. We set five groups corresponding to the healthy sleep score of 5, 4, 3, 2, and 0-1, respectively. The primary outcome was the incidence of overall CMM among enrolled hypertensives. We assessed the adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) by Fine-Gray subdistribution hazard models.</p>
RESULTS: We found the full-adjusted HR (95% CI) for overall CMM was 0.93 (0.91-0.95) for a 1-point increase in the healthy sleep score. Compared to hypertensives with a healthy sleep score of 0-1, those with a score of 5 had a 27% lower risk of overall CMM, and 37%, 23%, and 20% lower risks of diabetes mellitus, coronary heart disease, and stroke, respectively, after adjusting for sociodemographic characteristic, lifestyle, and clinical factors.</p>
CONCLUSIONS: Our results indicated that a healthy sleep pattern was associated with lower risks of CMM outcomes among hypertensives.</p>
7 Authors
- Lingfang He
- Tianqi Ma
- Jinchen Li
- Yi Luo
- Guogang Zhang
- Xunjie Cheng
- Yongping Bai
1 Application
| Application ID | Title |
|---|---|
| 76118 | Risk and Protective Factors Associated with Cardiometabolic Multimorbidity. |
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