| Title: | Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits |
| Journal: | Nature Genetics |
| Published: | 19 Dec 2016 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/27992416/ |
| DOI: | https://doi.org/10.1038/ng.3749 |
| URL: | https://kclpure.kcl.ac.uk/ws/files/86862675/Genome_wide_association_analyses_LANE_PublishedFebruary2017_GREEN_AAM.pdf |
| Citations: | 307 (56 in last 2 years) as of 8 Aug 2024 |
Publication 746
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Abstract
Richa Saxena and colleagues report genome-wide association analyses of sleep disturbance traits in the UK Biobank cohort. They discover loci associated with insomnia symptoms and excessive daytime sleepiness and identify genetic correlations with several neuropsychiatric and metabolic traits.</p>
16 Keywords
- Adiposity
- Adult
- Aged
- Female
- Genetic Loci
- Genome-Wide Association Study
- Humans
- Male
- Mental Disorders
- Metabolic Diseases
- Middle Aged
- Phenotype
- Self Report
- Sleep
- Sleep Wake Disorders
- Waist Circumference
20 Authors
- Jacqueline M Lane
- Jingjing Liang
- Irma Vlasac
- Simon G Anderson
- David A Bechtold
- Jack Bowden
- Richard Emsley
- Shubhroz Gill
- Max A Little
- Annemarie I Luik
- Andrew Loudon
- Frank A J L Scheer
- Shaun M Purcell
- Simon D Kyle
- Deborah A Lawlor
- Xiaofeng Zhu
- Susan Redline
- David W Ray
- Martin K Rutter
- Richa Saxena
1 Application
| Application ID | Title |
|---|---|
| 6818 | Sleep and chronotype and their causal links with cardiometabolic and chronic inflammatory diseases |
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