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Abstract
Exome-wide genetic analysis on >300,000 individuals identifies associations with plasma lipid traits. Loci significantly associated with cholesterol and triglycerides are examined together to determine the effects of alleles on type 2 diabetes and coronary artery disease risk.</p>
227 Authors
Dajiang J Liu
Gina M Peloso
Haojie Yu
Adam S Butterworth
Xiao Wang
Anubha Mahajan
Danish Saleheen
Connor Emdin
Dewan Alam
Alexessander Couto Alves
Philippe Amouyel
Emanuele Di Angelantonio
Dominique Arveiler
Themistocles L Assimes
Paul L Auer
Usman Baber
Christie M Ballantyne
Lia E Bang
Marianne Benn
Joshua C Bis
Michael Boehnke
Eric Boerwinkle
Jette Bork-Jensen
Erwin P Bottinger
Ivan Brandslund
Morris Brown
Fabio Busonero
Mark J Caulfield
John C Chambers
Daniel I Chasman
Y Eugene Chen
Yii-Der Ida Chen
Rajiv Chowdhury
Cramer Christensen
Audrey Y Chu
John M Connell
Francesco Cucca
L Adrienne Cupples
Scott M Damrauer
Gail Davies
Ian J Deary
George Dedoussis
Joshua C Denny
Anna Dominiczak
Marie-Pierre Dubé
Tapani Ebeling
Gudny Eiriksdottir
Tõnu Esko
Aliki-Eleni Farmaki
Mary F Feitosa
Marco Ferrario
Jean Ferrieres
Ian Ford
Myriam Fornage
Paul W Franks
Timothy M Frayling
Ruth Frikke-Schmidt
Lars G Fritsche
Philippe Frossard
Valentin Fuster
Santhi K Ganesh
Wei Gao
Melissa E Garcia
Christian Gieger
Franco Giulianini
Mark O Goodarzi
Harald Grallert
Niels Grarup
Leif Groop
Megan L Grove
Vilmundur Gudnason
Torben Hansen
Tamara B Harris
Caroline Hayward
Joel N Hirschhorn
Oddgeir L Holmen
Jennifer Huffman
Yong Huo
Kristian Hveem
Sehrish Jabeen
Anne U Jackson
Johanna Jakobsdottir
Marjo-Riitta Jarvelin
Gorm B Jensen
Marit E Jørgensen
J Wouter Jukema
Johanne M Justesen
Pia R Kamstrup
Stavroula Kanoni
Fredrik Karpe
Frank Kee
Amit V Khera
Derek Klarin
Heikki A Koistinen
Jaspal S Kooner
Charles Kooperberg
Kari Kuulasmaa
Johanna Kuusisto
Markku Laakso
Timo Lakka
Claudia Langenberg
Anne Langsted
Lenore J Launer
Torsten Lauritzen
David C M Liewald
Li An Lin
Allan Linneberg
Ruth J F Loos
Yingchang Lu
Xiangfeng Lu
Reedik Mägi
Anders Malarstig
Ani Manichaikul
Alisa K Manning
Pekka Mäntyselkä
Eirini Marouli
Nicholas G D Masca
Andrea Maschio
James B Meigs
Olle Melander
Andres Metspalu
Andrew P Morris
Alanna C Morrison
Antonella Mulas
Martina Müller-Nurasyid
Patricia B Munroe
Matt J Neville
Jonas B Nielsen
Sune F Nielsen
Børge G Nordestgaard
Jose M Ordovas
Roxana Mehran
Christoper J O'Donnell
Marju Orho-Melander
Cliona M Molony
Pieter Muntendam
Sandosh Padmanabhan
Colin N A Palmer
Dorota Pasko
Aniruddh P Patel
Oluf Pedersen
Markus Perola
Annette Peters
Charlotta Pisinger
Giorgio Pistis
Ozren Polasek
Neil Poulter
Bruce M Psaty
Daniel J Rader
Asif Rasheed
Rainer Rauramaa
Dermot F Reilly
Alex P Reiner
Frida Renström
Stephen S Rich
Paul M Ridker
John D Rioux
Neil R Robertson
Dan M Roden
Jerome I Rotter
Igor Rudan
Veikko Salomaa
Nilesh J Samani
Serena Sanna
Naveed Sattar
Ellen M Schmidt
Robert A Scott
Peter Sever
Raquel S Sevilla
Christian M Shaffer
Xueling Sim
Suthesh Sivapalaratnam
Kerrin S Small
Albert V Smith
Blair H Smith
Sangeetha Somayajula
Lorraine Southam
Timothy D Spector
Elizabeth K Speliotes
John M Starr
Kathleen E Stirrups
Nathan Stitziel
Konstantin Strauch
Heather M Stringham
Praveen Surendran
Hayato Tada
Alan R Tall
Hua Tang
Jean-Claude Tardif
Kent D Taylor
Stella Trompet
Philip S Tsao
Jaakko Tuomilehto
Anne Tybjaerg-Hansen
Natalie R van Zuydam
Anette Varbo
Tibor V Varga
Jarmo Virtamo
Melanie Waldenberger
Nan Wang
Nick J Wareham
Helen R Warren
Peter E Weeke
Joshua Weinstock
Jennifer Wessel
James G Wilson
Peter W F Wilson
Ming Xu
Hanieh Yaghootkar
Robin Young
Eleftheria Zeggini
He Zhang
Neil S Zheng
Weihua Zhang
Yan Zhang
Wei Zhou
Yanhua Zhou
Magdalena Zoledziewska
Joanna M M Howson
John Danesh
Mark I McCarthy
Chad A Cowan
Goncalo Abecasis
Panos Deloukas
Kiran Musunuru
Cristen J Willer
Sekar Kathiresan
Enabling scientific discoveries that improve human health