The UK Biobank receives death notifications on a regular basis through linkage to national death registries. In this report we present summary statistics on the most common causes of death within the UK Biobank cohort.
The main cause of death for each participant is identified by the ICD10 code. To align with researcher interests we present summary statistics for grouped ICD10 codes (see Appendix 1). Please visit UKBiobank Showcase website to see numbers of deaths for each unique ICD10 code.
This report includes complete follow-up up to the current UK Biobank censoring date for death registry data.
This document was created on the 24 May, 2022.
Since recruitment, 37733 UK Biobank participants have died, with a mean age at death of 69.6 years. Men constitute 59% of deaths but are on average 5 months older than women when they die.
Sex | N | Percent | Mean Age at Death |
---|---|---|---|
F | 15384 | 41 | 69.4 |
M | 22349 | 59 | 69.8 |
The main cause of death for each participant is identified by the ICD10 code. In this analysis we do not consider deaths due to benign cancers.
Figure 1: Numbers of the 20 most common causes of death within
the UK Biobank cohort
Figure 2: Numbers of the 20 most common causes of death within
the UK Biobank cohort by sex
GroupedCause | <50 years | 50 - 60 years | 60 - 70 years | 70+ years | Total |
---|---|---|---|---|---|
Ischemic heart disease | 43 | 405 | 1497 | 2096 | 4041 |
Lung cancer | 26 | 274 | 1289 | 1658 | 3247 |
Colorectal cancer | 22 | 249 | 641 | 894 | 1806 |
Cerebrovascular disease | 9 | 107 | 464 | 1039 | 1619 |
Dementia | 0 | 11 | 172 | 1417 | 1600 |
Breast cancer | 65 | 306 | 616 | 486 | 1473 |
Pancreatic cancer | 12 | 128 | 516 | 745 | 1401 |
COVID19 | 0 | 47 | 192 | 919 | 1158 |
Prostate cancer | 1 | 37 | 333 | 730 | 1101 |
Emphysema, chronic obstructive pulmonary disease | 4 | 42 | 316 | 686 | 1048 |
Injury and other external causes | 82 | 225 | 338 | 358 | 1003 |
Oesophageal cancer | 6 | 90 | 359 | 447 | 902 |
Brain cancer | 23 | 135 | 367 | 317 | 842 |
Lymphoma | 8 | 56 | 229 | 419 | 712 |
Ovarian cancer | 10 | 83 | 260 | 315 | 668 |
Liver cancer | 4 | 66 | 235 | 343 | 648 |
Interstitial pulmonary diseases | 2 | 21 | 165 | 446 | 634 |
Leukaemia | 9 | 50 | 198 | 344 | 601 |
Other diseases of the digestive system | 10 | 68 | 197 | 312 | 587 |
Pneumonia | 6 | 40 | 177 | 348 | 571 |
Top 20 Causes Total | 342 | 2440 | 8561 | 14319 | 25662 |
Other Causes Total | 223 | 1161 | 3513 | 5919 | 10816 |
GroupedCause | 2006 - 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | Total |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ischemic heart disease | 386 | 204 | 217 | 254 | 261 | 302 | 338 | 404 | 383 | 390 | 472 | 430 | 1322 |
Lung cancer | 277 | 190 | 234 | 254 | 263 | 272 | 259 | 324 | 284 | 326 | 321 | 243 | 1218 |
Colorectal cancer | 132 | 122 | 119 | 117 | 147 | 144 | 165 | 156 | 147 | 190 | 221 | 146 | 637 |
Breast cancer | 170 | 114 | 96 | 122 | 117 | 108 | 127 | 117 | 121 | 126 | 161 | 94 | 619 |
Cerebrovascular disease | 95 | 55 | 76 | 85 | 125 | 100 | 139 | 132 | 171 | 203 | 242 | 196 | 436 |
Pancreatic cancer | 97 | 59 | 88 | 84 | 99 | 117 | 118 | 142 | 151 | 144 | 161 | 141 | 427 |
Injury and other external causes | 116 | 64 | 74 | 81 | 86 | 100 | 100 | 77 | 122 | 61 | 69 | 53 | 421 |
Prostate cancer | 64 | 60 | 52 | 67 | 92 | 94 | 94 | 117 | 110 | 129 | 124 | 98 | 335 |
Brain cancer | 79 | 55 | 60 | 70 | 56 | 81 | 74 | 62 | 84 | 92 | 74 | 55 | 320 |
Oesophageal cancer | 74 | 44 | 58 | 59 | 70 | 74 | 72 | 74 | 106 | 86 | 93 | 92 | 305 |
Lymphoma | 51 | 38 | 46 | 40 | 65 | 72 | 57 | 61 | 63 | 71 | 77 | 71 | 240 |
Ovarian cancer | 56 | 43 | 40 | 55 | 46 | 56 | 57 | 59 | 59 | 64 | 83 | 50 | 240 |
Emphysema, chronic obstructive pulmonary disease | 46 | 30 | 42 | 46 | 60 | 80 | 96 | 118 | 128 | 167 | 122 | 113 | 224 |
Leukaemia | 40 | 30 | 33 | 38 | 61 | 55 | 61 | 33 | 56 | 72 | 75 | 47 | 202 |
Liver cancer | 39 | 35 | 35 | 40 | 51 | 58 | 51 | 69 | 56 | 68 | 75 | 71 | 200 |
Other diseases of the digestive system | 44 | 22 | 28 | 31 | 48 | 40 | 60 | 53 | 51 | 61 | 88 | 61 | 173 |
Interstitial pulmonary diseases | 23 | 19 | 30 | 42 | 49 | 38 | 63 | 73 | 62 | 86 | 84 | 65 | 163 |
Pneumonia | 29 | 11 | 24 | 26 | 34 | 60 | 57 | 50 | 89 | 84 | 66 | 41 | 124 |
Dementia | 5 | 9 | 21 | 41 | 38 | 65 | 118 | 155 | 227 | 268 | 348 | 305 | 114 |
COVID19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 697 | 461 | 0 |
Top 20 Causes Total | 1823 | 1204 | 1373 | 1552 | 1768 | 1916 | 2106 | 2276 | 2470 | 2688 | 3653 | 2833 | 7720 |
Other Causes Total | 742 | 496 | 512 | 692 | 735 | 823 | 946 | 1058 | 1117 | 1228 | 1335 | 1132 | 3258 |
GroupedCause | ICD10_codes |
---|---|
Oesophageal cancer | C15 |
Colorectal cancer | C18, C19, C20 |
Liver cancer | C22 |
Pancreatic cancer | C25 |
Lung cancer | C33, C34 |
Breast cancer | C50 |
Ovarian cancer | C56 |
Prostate cancer | C61 |
Brain cancer | C71 |
Lymphoma | C81, C82, C83, C84, C85, C86, C88 |
Leukaemia | C91, C92, C93, C94, C95 |
Dementia | F01, F03, F05, G30, G31 |
Ischemic heart disease | I20, I21, I24, I25 |
Cerebrovascular disease | I60, I61, I62, I63, I64, I67, I69 |
Pneumonia | J12, J13, J15, J18 |
Emphysema, chronic obstructive pulmonary disease | J43, J44 |
Interstitial pulmonary diseases | J80, J81, J82, J84 |
Other diseases of the digestive system | K31, K61, K62, K63, K71, K72, K74, K75, K76, K80, K81, K82, K83, K85, K86, K90, K92 |
COVID19 | U07 |
Injury and other external causes | V03, V04, V05, V09, V13, V14, V18, V19, V20, V23, V27, V28, V29, V42, V43, V44, V47, V48, V49, V80, V89, V92, V93, V95, V96, V97, W00, W01, W05, W06, W07, W08, W10, W11, W13, W15, W17, W19, W20, W22, W55, W65, W67, W70, W74, W76, W78, W79, W80, W84, W87, W94, X00, X04, X08, X09, X11, X16, X23, X31, X40, X41, X42, X44, X45, X47, X49, X59, X60, X61, X62, X63, X64, X67, X69, X70, X71, X73, X74, X76, X78, X80, X81, X83, X84, X99, Y10, Y11, Y12, Y13, Y14, Y17, Y20, Y21, Y28, Y30, Y31, Y34, Y40, Y44, Y60, Y65, Y83, Y84, Y85, Y86, Y87, Y88 |