| Title: | Case-control association mapping by proxy using family history of disease |
| Journal: | Nature Genetics |
| Published: | 16 Jan 2017 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/28092683/ |
| DOI: | https://doi.org/10.1038/ng.3766 |
| URL: | https://www.biorxiv.org/content/biorxiv/early/2016/06/17/045831.full.pdf |
Publication 703
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Abstract
Jimmy Liu and colleagues perform genome-wide association by proxy (GWAX) in a large population cohort by replacing cases with their first-degree relatives. They apply GWAX to 12 common diseases and show its utility by identifying new risk loci for Alzheimer's disease, coronary artery disease and type 2 diabetes.</p>
3 Authors
- Jimmy Z Liu
- Yaniv Erlich
- Joseph K Pickrell
1 Application
| Application ID | Title |
|---|---|
| 11138 | Genomic and evolutionary analyses of common disease in a large cohort |
Enabling scientific discoveries that improve human health