| Title: | Road Traffic Noise, Obesity, and the Risk of Incident Type 2 Diabetes: A Cohort Study in UK Biobank |
| Journal: | International Journal of Public Health |
| Published: | 12 Oct 2022 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/36312318/ |
| DOI: | https://doi.org/10.3389/ijph.2022.1605256 |
| URL: | https://www.ssph-journal.org/articles/10.3389/ijph.2022.1605256/pdf |
Publication 10563
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Abstract
Objectives: To assess the association of road traffic noise exposure with Type 2 Diabetes (T2D) risk, and to explore the potential moderation effect of obesity. Methods: A total of 305,969 participants from the UK Biobank Cohort - an open access cohort of 500,000 participants recruited in the United Kingdom (UK) between 2006 and 2010 - were included in the study. A Cox proportional hazard model was fitted to assess the association between road traffic noise exposure and T2D. Results: A total of 19,303 participants were diagnosed with T2D during the 11.9-year median follow-up period. For every 10 dB increase in road traffic noise, there was a 4% increase in T2D risk (HR = 1.04, 95%CI: 1.01, 1.07). Besides, a significant positive interaction was observed between obesity and road traffic noise (P interaction <0.001) for the risk of T2D. The association of road traffic noise with T2D was stronger in overweight and obese participants (HR = 1.04, 95% CI: 1.01-1.08), but not significant among lean ones (HR = 0.96, 95% CI: 0.86-1.07). Conclusion: Our study observed a longitudinal association of road traffic noise exposure with T2D risk, which was stronger among overweight and obese individuals than the lean ones.</p>
11 Authors
- Lei Zuo
- Xia Chen
- Mingliang Liu
- Li Chen
- Wenbin Xu
- Haiyan Chen
- Shan Dong
- Yuan Wei
- Liangming Li
- Shuang Peng
- Guang Hao
1 Application
| Application ID | Title |
|---|---|
| 69597 | Association of Noise Pollution and Cardiometabolic Disease |
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