| Title: | Wearable device-measured bouted and sporadic physical activity patterns and incident COPD: A prospective cohort study from UK Biobank |
| Journal: | Public Health |
| Published: | 7 Nov 2024 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/39515216/ |
| DOI: | https://doi.org/10.1016/j.puhe.2024.10.027 |
Publication 14197
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Abstract
OBJECTIVES: Moderate-to-vigorous physical activity (MVPA) is associated with a reduced risk of chronic obstructive pulmonary disease (COPD), but the optimal accumulation patterns are unclear. We aimed to investigate the associations between accelerometer-measured bouted and sporadic MVPA and incident COPD in the UK Biobank.</p>
STUDY DESIGN: Prospective cohort study.</p>
METHODS: We included 94161 COPD-free participants (median age of 61.74 years at baseline) from the UK Biobank who wore a wrist accelerometer. A random forest classifier was used to differentiate sporadic and bouted MVPA. Multivariable Cox proportional hazard models and restricted cubic splines were used to examine the MVPA-COPD associations.</p>
RESULTS: During a median follow-up of 7.95 years, 1380 incident COPD cases were identified. Bouted MVPA was inversely associated with COPD incidence in an L-shaped manner, with hazard ratios of 0.62 (95 % CI: 0.52-0.75) for intermediate vs lowest quintile and 0.43 (95 % CI: 0.34-0.55) for highest vs lowest quintile. In those with insufficient bouted MVPA, sporadic MVPA had a U-shaped association with incident COPD, with hazard ratios of 0.82 (95 %: CI: 0.67-0.99) for intermediate vs lowest quintile and 1.11 (95 % CI: 0.88-1.39) for highest vs lowest quintile.</p>
CONCLUSIONS: Bouted MVPA is a key factor in reducing COPD incidence, while modest sporadic MVPA may offer protection when bouted MVPA is insufficient.</p>
15 Keywords
- Accelerometry
- Aged
- Biological Specimen Banks
- Exercise
- Female
- Humans
- Incidence
- Male
- Middle Aged
- Proportional Hazards Models
- Prospective Studies
- Pulmonary Disease, Chronic Obstructive
- UK Biobank
- United Kingdom
- Wearable Electronic Devices
5 Authors
- Qingling Yang
- Tongyu Ma
- Kin Cheung
- Harry Haoxiang Wang
- Yao Jie Xie
1 Application
| Application ID | Title |
|---|---|
| 85118 | Time-of-day physical activity and health outcomes |
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