| Title: | Sleep Pattern, Lifestyle Pattern, and Risks of Overall and 20 Types of Cancers: Findings From the UK Biobank Cohort |
| Journal: | International Journal of Public Health |
| Published: | 17 Jan 2025 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/39896234/ |
| DOI: | https://doi.org/10.3389/ijph.2024.1607726 |
Publication 14491
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Abstract
Objectives: Sleep health and other lifestyle behaviours are gaining increasing attention in public health, particularly for cancer prevention, but a comprehensive assessment is lacking.</p>
Methods: The study included 380,042 UK Biobank participants. A healthy sleep score was constructed based on five sleep factors: chronotype, sleep duration, insomnia, snoring, and daytime dozing. A healthy lifestyle score was constructed based on four lifestyle factors: smoking, alcohol consumption, diet and physical activity. The effect of healthy sleep and lifestyle on cancer risk was examined by Cox proportional hazard models.</p>
Results: Both healthy sleep and lifestyle patterns were significantly associated with a reduced risk of overall cancer and specific cancer sites. Participants with healthy sleep and lifestyle patterns had a lower risk of overall cancer (HR = 0.72, 95% CI = 0.68-0.77), liver cancer (HR = 0.53, 95% CI = 0.31-0.90), bladder cancer (HR = 0.61, 95% CI = 0.47-0.79), lung cancer (HR = 0.22, 95% CI = 0.19-0.27), and colorectal cancer (HR = 0.80, 95% CI = 0.66-0.96) compared to those with unhealthy patterns.</p>
Conclusion: Our findings highlight the importance of public health education and interventions to improve sleep and other lifestyle behaviours for cancer prevention.</p>
19 Keywords
- Adult
- Aged
- Alcohol Drinking
- Biological Specimen Banks
- Cohort Studies
- Exercise
- Female
- Healthy Lifestyle
- Humans
- Life Style
- Male
- Middle Aged
- Neoplasms
- Proportional Hazards Models
- Risk Factors
- Sleep
- Smoking
- UK Biobank
- United Kingdom
12 Authors
- Yue-Ze Zhao
- Wen-Li Zhang
- Kai-Wen Zhang
- Yong-Qiao He
- Wen-Qiong Xue
- Da-Wei Yang
- Hua Diao
- Ruo-Wen Xiao
- Ying Liao
- Qiao-Ling Wang
- Wei-Hua Jia
- Tong-Min Wang
1 Application
| Application ID | Title |
|---|---|
| 58450 | Risk prediction and prognosis models based on genetic, environmental and clinical determinants for noncommunicable diseases |
Enabling scientific discoveries that improve human health