| Title: | Determining the atlas correspondence of Desikan-Killiany-Tourville and Glasser MMP1 atlases across magnetic field strengths |
| Journal: | Journal of Neuroscience Methods |
| Published: | 3 Apr 2025 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/40187536/ |
| DOI: | https://doi.org/10.1016/j.jneumeth.2025.110445 |
Publication 14780
WARNING: the interactive features of this website use CSS3, which your browser does not support. To use the full features of this website, please update your browser.
Abstract
BACKGROUND: Over sixty-six brain atlases exist to parcellate the brain based on cytoarchitecture, function, and connectivity. Because atlas choice depends on individual study goals and hypotheses, variability in findings contributes to challenges in replication, validation, and reconciling the results across studies. Our goal was to measure the intersection of three commonly used atlases and create a tool to find regional correspondence between the atlases.</p>
NEW METHOD: This study used three independent samples of anatomical MRI data acquired with different B0 magnetic field strengths: 1.5 Tesla (T), 3 T, and 7 T. The Desikan-Killiany- Tourville (DKT) and Glasser atlases were used to parcellate the brain. Coefficient-of- variation of regional volumes was measured to evaluate regional variability across subjects in each atlas. DKT and Glasser parcellation correspondence was calculated to answer the shared question of what Glasser regions intersect with a DKT region and vice versa and to investigate consistency of the parcellations in relation to each other across a variety of individuals and image resolutions.</p>
RESULTS: We found that regional correspondence was consistent across field strengths for the DKT and Glasser parcellations despite showing population variability in volume, age, and sex, and was validated in the Schaefer400 atlas. Parcellation intersection data along with sample code to calculate specific regional correspondence is available.</p>
COMPARISON WITH EXISTING METHODS: Prior studies have attempted to reconcile multiple atlases, but did not compare voxel- by-voxel on real data.</p>
CONCLUSION: This analysis created a tool for researchers and can aid in comparisons with differing atlas choice and variable field strengths.</p>
12 Keywords
- Adult
- Atlases as Topic
- Brain
- Brain Mapping
- Female
- Humans
- Image Processing, Computer-Assisted
- Magnetic Fields
- Magnetic Resonance Imaging
- Male
- Middle Aged
- Young Adult
4 Authors
- Madison Lewis
- Nicholas Theis
- Nidhi Girish
- Konasale Prasad
1 Application
| Application ID | Title |
|---|---|
| 68923 | Multiplex brain network architecture in psychoses |
Enabling scientific discoveries that improve human health