| Title: | The impact of menopausal hormone therapy (MHT) on cardiac structure and function: Insights from the UK Biobank imaging enhancement study |
| Journal: | PLoS One |
| Published: | 8 Mar 2018 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/29518141/ |
| DOI: | https://doi.org/10.1371/journal.pone.0194015 |
Publication 2365
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Abstract
The effect of menopausal hormone therapy (MHT) previously known as hormone replacement therapy on cardiovascular health remains unclear and controversial. This cross-sectional study examined the impact of MHT on left ventricular (LV) and left atrial (LA) structure and function, alterations in which are markers of subclinical cardiovascular disease, in the UK Biobank population-based cohort. In this large cohort of post-menopausal women free of cardiovascular disease, use of MHT was not associated with adverse, subclinical changes in cardiac structure and function. The findings provide a novel way to examine the impact of MHT on the cardiovascular system and future work will focus upon linkage of MHT use and CMR parameters to cardiovascular outcome data.1 Author
- Sanghvi MM et al.
1 Application
| Application ID | Title |
|---|---|
| 2964 | Description of cardiovascular phenotype in the UK Biobank population based on cardiovascular magnetic resonance and carotid ultrasound |
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