| Title: | Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke |
| Journal: | Nat Commun |
| Published: | 20 Dec 2019 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/31862893/ |
| DOI: | https://doi.org/10.1038/s41467-019-13848-1 |
Publication 2385
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Abstract
We have developed a genomic risk score for ischaemic stroke and tested this score in the UK Biobank. Our score was similarly or more predictive compared to several risk factors, such as family history, blood pressure, body mass index, and smoking. We estimate the reductions needed in modifiable risk factors for individuals with different levels of genomic risk and suggest that, for individuals with high genomic risk, achieving risk factor levels recommended by current guidelines may be insufficient to mitigate risk.1 Author
- Abraham G et al.
1 Application
| Application ID | Title |
|---|---|
| 26865 | Risk factors for `less-frequent` cardiovascular diseases |
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