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Abstract
Tooth decay and periodontitis (gum disease) are complex diseases which continue to be major problems worldwide. Although researchers know that genetic factors influence risk of dental problems, it has been difficult to identify specific genes which are responsible. This study aimed to use detailed clinical records of dental diseases in a consortium called GLIDE in conjunction with questionnaire data in UK Biobank to identify genes which are linked to dental problems. The research discovered 47 new links between genes and tooth decay which may lead to a better understanding of the biology of tooth decay.