| Title: | Genome-wide association study identifies loci for arterial stiffness index in 127,121 UK Biobank participants |
| Journal: | Sci Rep |
| Published: | 24 Jun 2019 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/31235810/ |
| DOI: | https://doi.org/10.1038/s41598-019-45703-0 |
Publication 2856
WARNING: the interactive features of this website use CSS3, which your browser does not support. To use the full features of this website, please update your browser.
Abstract
In this large study that included 127,121 participants in the UK Biobank, we found genetic variations that are associated with arterial stiffness index (ASI), a measure of blood vessel stiffness using intra-red finger probes. Our findings give us a better understanding of the mechanisms that contribute towards blood vessel stiffness. This is important as we know that stiffer blood vessels are associated with high blood pressure, heart diseases and stroke. Therefore, the additional knowledge gained from this study will help with better disease prediction and treatment.1 Author
- Fung K et al.
1 Application
| Application ID | Title |
|---|---|
| 2964 | Description of cardiovascular phenotype in the UK Biobank population based on cardiovascular magnetic resonance and carotid ultrasound |
Enabling scientific discoveries that improve human health