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Abstract
Using UKBiobank and genetic variants for 25(OH)D (from the Jiang et al 2018 GWAS) to perform Mendelian Randomisation, we have found no evidence that maternal circulating 25(OH)D affects offspring birth weight. We also used genetic variants for serum Calcium (from the O Seaghdha et al 2013 GWAS) to perform Mendelian Randomisation, and we found no evidence of that maternal circulating Calcium affects offspring birth weight in the main analyses, however we did find evidence of masking horizontal pleiotropy.