| Title: | Common brain disorders are associated with heritable patterns of apparent aging of the brain |
| Journal: | Nat Neurosci |
| Published: | 1 Oct 2019 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/31551603/ |
| DOI: | https://doi.org/10.1038/s41593-019-0471-7 |
Publication 3113
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Abstract
Common risk factors for psychiatric and other brain disorders are likely to converge on biological pathways influencing the development and maintenance of brain structure and function across life. Using structural MRI data from 45,615 individuals aged 3 96 years, we demonstrate distinct patterns of apparent brain aging in several brain disorders and reveal genetic pleiotropy between apparent brain aging in healthy individuals and common brain disorders.1 Author
- Kaufmann T et al.
1 Application
| Application ID | Title |
|---|---|
| 27412 | Boosting the power of GWAS using novel statistical tools |
Enabling scientific discoveries that improve human health