| Title: | Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses |
| Journal: | Nature Genetics |
| Published: | 18 Apr 2016 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/27089181/ |
| DOI: | https://doi.org/10.1038/ng.3552 |
| URL: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884152 |
| Citations: | 900 (135 in last 2 years) as of 8 Aug 2024 |
Publication 719
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Abstract
Daniel Benjamin, Meike Bartels, Philipp Koellinger and colleagues report a genome-wide association meta-analysis of subjective well-being, depressive symptoms and neuroticism. The study leverages a large sample size together with genetic correlations between the phenotypes to identify, with high confidence, loci associated with each phenotype.</p>
8 Keywords
- Anxiety Disorders
- Bayes Theorem
- Depression
- Genome-Wide Association Study
- Humans
- Neuroticism
- Phenotype
- Polymorphism, Single Nucleotide
187 Authors
- Aysu Okbay
- Bart M L Baselmans
- Jan-Emmanuel De Neve
- Patrick Turley
- Michel G Nivard
- Mark Alan Fontana
- S Fleur W Meddens
- Richard Karlsson Linnér
- Cornelius A Rietveld
- Jaime Derringer
- Jacob Gratten
- James J Lee
- Jimmy Z Liu
- Ronald de Vlaming
- Tarunveer S Ahluwalia
- Jadwiga Buchwald
- Alana Cavadino
- Alexis C Frazier-Wood
- Nicholas A Furlotte
- Victoria Garfield
- Marie Henrike Geisel
- Juan R Gonzalez
- Saskia Haitjema
- Robert Karlsson
- Sander W van der Laan
- Karl-Heinz Ladwig
- Jari Lahti
- Sven J van der Lee
- Penelope A Lind
- Tian Liu
- Lindsay Matteson
- Evelin Mihailov
- Michael B Miller
- Camelia C Minica
- Ilja M Nolte
- Dennis Mook-Kanamori
- Peter J van der Most
- Christopher Oldmeadow
- Yong Qian
- Olli Raitakari
- Rajesh Rawal
- Anu Realo
- Rico Rueedi
- Börge Schmidt
- Albert V Smith
- Evie Stergiakouli
- Toshiko Tanaka
- Kent Taylor
- Gudmar Thorleifsson
- Juho Wedenoja
- Juergen Wellmann
- Harm-Jan Westra
- Sara M Willems
- Wei Zhao
- Najaf Amin
- Andrew Bakshi
- Sven Bergmann
- Gyda Bjornsdottir
- Patricia A Boyle
- Samantha Cherney
- Simon R Cox
- Gail Davies
- Oliver S P Davis
- Jun Ding
- Nese Direk
- Peter Eibich
- Rebecca T Emeny
- Ghazaleh Fatemifar
- Jessica D Faul
- Luigi Ferrucci
- Andreas J Forstner
- Christian Gieger
- Richa Gupta
- Tamara B Harris
- Juliette M Harris
- Elizabeth G Holliday
- Jouke-Jan Hottenga
- Philip L De Jager
- Marika A Kaakinen
- Eero Kajantie
- Ville Karhunen
- Ivana Kolcic
- Meena Kumari
- Lenore J Launer
- Lude Franke
- Ruifang Li-Gao
- David C Liewald
- Marisa Koini
- Anu Loukola
- Pedro Marques-Vidal
- Grant W Montgomery
- Miriam A Mosing
- Lavinia Paternoster
- Alison Pattie
- Katja E Petrovic
- Laura Pulkki-Råback
- Lydia Quaye
- Katri Räikkönen
- Igor Rudan
- Rodney J Scott
- Jennifer A Smith
- Angelina R Sutin
- Maciej Trzaskowski
- Anna E Vinkhuyzen
- Lei Yu
- Delilah Zabaneh
- John R Attia
- David A Bennett
- Klaus Berger
- Lars Bertram
- Dorret I Boomsma
- Harold Snieder
- Shun-Chiao Chang
- Francesco Cucca
- Ian J Deary
- Cornelia M van Duijn
- Johan G Eriksson
- Ute Bültmann
- Eco J C de Geus
- Patrick J F Groenen
- Vilmundur Gudnason
- Torben Hansen
- Catharine A Hartman
- Claire M A Haworth
- Caroline Hayward
- Andrew C Heath
- David A Hinds
- Elina Hyppönen
- William G Iacono
- Marjo-Riitta Järvelin
- Karl-Heinz Jöckel
- Jaakko Kaprio
- Sharon L R Kardia
- Liisa Keltikangas-Järvinen
- Peter Kraft
- Laura D Kubzansky
- Terho Lehtimäki
- Patrik K E Magnusson
- Nicholas G Martin
- Matt McGue
- Andres Metspalu
- Melinda Mills
- Renée de Mutsert
- Albertine J Oldehinkel
- Gerard Pasterkamp
- Nancy L Pedersen
- Robert Plomin
- Ozren Polasek
- Christine Power
- Stephen S Rich
- Frits R Rosendaal
- Hester M den Ruijter
- David Schlessinger
- Helena Schmidt
- Rauli Svento
- Reinhold Schmidt
- Behrooz Z Alizadeh
- Thorkild I A Sørensen
- Tim D Spector
- John M Starr
- Kari Stefansson
- Andrew Steptoe
- Antonio Terracciano
- Unnur Thorsteinsdottir
- A Roy Thurik
- Nicholas J Timpson
- Henning Tiemeier
- André G Uitterlinden
- Peter Vollenweider
- Gert G Wagner
- David R Weir
- Jian Yang
- Dalton C Conley
- George Davey Smith
- Albert Hofman
- Magnus Johannesson
- David I Laibson
- Sarah E Medland
- Michelle N Meyer
- Joseph K Pickrell
- Tõnu Esko
- Robert F Krueger
- Jonathan P Beauchamp
- Philipp D Koellinger
- Daniel J Benjamin
- Meike Bartels
- David Cesarini
1 Application
| Application ID | Title |
|---|---|
| 11425 | The Social Science Genetic Association Consortium |
Enabling scientific discoveries that improve human health