| Title: | Physical and neurobehavioral determinants of reproductive onset and success |
| Journal: | Nature Genetics |
| Published: | 18 Apr 2016 |
| Pubmed: | https://pubmed.ncbi.nlm.nih.gov/27089180/ |
| DOI: | https://doi.org/10.1038/ng.3551 |
| URL: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238953 |
| Citations: | 125 (22 in last 2 years) as of 8 Aug 2024 |
Publication 7552
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Abstract
John Perry, Ken Ong and colleagues perform a genome-wide association study for reproductive ability, behavior and success to determine underlying genetic factors. They find 38 variants associated with age of first sexual intercourse and show that both physical and neurobehavioral traits influence the onset of reproductive activity.</p>
18 Keywords
- Adolescent
- Adult
- Age Factors
- Behavior
- Cell Adhesion Molecules
- Coitus
- Estrogen Receptor alpha
- Female
- Genome-Wide Association Study
- Humans
- Male
- Membrane Proteins
- Methionine Sulfoxide Reductases
- Nerve Tissue Proteins
- Puberty
- RNA-Binding Proteins
- Sexual Behavior
- Young Adult
18 Authors
- Felix R Day
- Hannes Helgason
- Daniel I Chasman
- Lynda M Rose
- Po-Ru Loh
- Robert A Scott
- Agnar Helgason
- Augustine Kong
- Gisli Masson
- Olafur Th Magnusson
- Daniel Gudbjartsson
- Unnur Thorsteinsdottir
- Julie E Buring
- Paul M Ridker
- Patrick Sulem
- Kari Stefansson
- Ken K Ong
- John R B Perry
Enabling scientific discoveries that improve human health