| Title: | Associations of genetic, socioeconomic status, lifestyle, and environmental factors with health outcomes |
| Lead Institution: | Southern Medical University |
| Principal investigator: |
Application 91019
WARNING: the interactive features of this website use CSS3, which your browser does not support. To use the full features of this website, please update your browser.
About
Aims: This project aims to (1) investigate the associations between genetic, socioeconomic status, (time-varying) lifestyle, environmental factors and health outcomes; (2) further determine potential routes among socioeconomic status, various exposures and health outcomes; (3) reveal the influence of covariate missing on estimates of associations and compare different imputation methods. Scientific rationale: As the population is aging, non-communicable diseases such as cardio-respiratory, metabolic, and neurodegeneration diseases are increasingly prevalent in these years. Previous studies have identified several determinants of the occurrence and mortality of diseases of middle- and old-aged individuals, including genetic factors, cigarette smoking, alcohol consumption, air pollution, diet, and physical activity, etc. Assessing the independent and joint effects of genetic factors, socioeconomic status, (time-varying) lifestyle, environmental factors on health outcomes and further elucidating the underlying mechanisms using statistical approaches would shed light on targeted interventions and promote healthy aging. Project duration: 36 months Public health impact: The findings of this project would have important implications on how to promote healthy aging and subsequently improve public health through targeted interventions.1 Publication
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 11850 | Joint effects of air pollution and genetic susceptibility on incident primary open-angle glaucoma | Hao-Neng Huang (+7) | 2024 | The Science of The Total Environment |
Enabling scientific discoveries that improve human health