Category 170
Exome sequences - Genomics


The first tranche of UK Biobank whole exome sequencing (WES) was made available for 50,000 UK Biobank participants in March 2019, and the data for an additional 150,000 participants was made available in October 2020. Initially data was computed using two protocols, FE and SPB, however these were replaced by a new improved unified OQFE pipeline when the additional 150,000 sequences were released (with the earlier values being reprocessedto match this).

Note that the original release of the SPB variant (Fields 23170-23174) was found to contain errors and has been replaced by corrected values in Fields 23175-23179. Both FE and SPB results are now obsolete and only the OQFE results should be used.

Fields 23141-23146 will eventually contain information on all the participants for whom exome sequencing is possible. It will only be possible to access the data for these fields in-situ via UK Biobank's Rsearch Access Platform.