| Pub ID | Title | Author(s) | Year | Journal |
|---|
| 3860 | A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure | Timothy M. Frayling (+25) | 2018 | Cell Reports |
| 3911 | A Mendelian Randomization Study Provides Evidence That Adiposity and Dyslipidemia Lead to Lower Urinary Albumin-to-Creatinine Ratio, a Marker of Microvascular Function | Francesco Casanova (+12) | 2020 | Diabetes |
| 12257 | A founder UMOD variant is a common cause of hereditary nephropathy in the British population | Manoj K Valluru (+65) | 2022 | Journal of Medical Genetics |
| 3886 | A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor | Harry D. Green (+8) | 2021 | PLOS Genetics |
| 3887 | A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin-creatinine ratio | Francesco Casanova (+10) | 2019 | Human Molecular Genetics |
| 14427 | A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data | Olivia Murrin (+24) | 2025 | EBioMedicine |
| 8639 | Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis | Pavel Loginovic (+14) | 2024 | Nature Communications |
| 10259 | BMI and well-being in people of East Asian and European ancestry: a Mendelian randomisation study | Jessica O'Loughlin (+11) | 2023 | Translational Psychiatry |
| 9575 | Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study | Vasilios Karageorgiou (+6) | 2023 | BMC Medicine |
| 4522 | CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits | Aurélien Macé (+105) | 2017 | Nature Communications |
| 16201 | Calculating genetic risk scores directly from summary statistics with an application to type 1 diabetes | Steven Squires (+2) | 2024 | Bioinformatics Advances |
| 9917 | Chromosome 20p11.2 deletions cause congenital hyperinsulinism via the loss of FOXA2 or its regulatory elements | Thomas W. Laver (+19) | 2024 | European Journal of Human Genetics |
| 9801 | Clustering of predicted loss-of-function variants in genes linked with monogenic disease can explain incomplete penetrance | Robin N. Beaumont (+3) | 2024 | Genome Medicine |
| 12590 | Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation | Susan Martin (+24) | 2022 | eLife |
| 4731 | Does Obesity Cause Thyroid Cancer? A Mendelian Randomization Study | Jonathan Mark Fussey (+5) | 2020 | The Journal of Clinical Endocrinology & Metabolism |
| 9149 | Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study | Francesco Casanova (+6) | 2023 | BMC Medicine |
| 15070 | Evaluating Genotype-Treatment Interactions for High-Risk Medications in British General Practice: Evidence from UK Biobank | Kinan Mokbel (+4) | 2025 | British Journal of General Practice |
| 15598 | Exploring the application of deep learning methods for polygenic risk score estimation | Steven Squires (+2) | 2025 | Biomedical Physics & Engineering Express |
| 4915 | Genetic Evidence for Different Adiposity Phenotypes and Their Opposing Influences on Ectopic Fat and Risk of Cardiometabolic Disease. | Susan Martin (+12) | 2021 | Diabetes |
| 11534 | Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood | Gareth Hawkes (+11) | 2023 | Diabetologia |
| 4916 | Genetic evidence that higher central adiposity causes gastro-oesophageal reflux disease: a Mendelian randomization study | Harry D Green (+11) | 2020 | International Journal of Epidemiology |
| 9870 | Genetic modifiers of rare variants in monogenic developmental disorder loci | Rebecca Kingdom (+4) | 2024 | Nature Genetics |
| 4928 | Genetic predictors of participation in optional components of UK Biobank | Jessica Tyrrell (+8) | 2021 | Nature Communications |
| 8826 | Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour | Samuel E. Jones (+31) | 2019 | Nature Communications |
| 13779 | Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile | Adrian H. Heald (+16) | 2021 | Diabetic Medicine |
| 12250 | Genetically proxied therapeutic prolyl-hydroxylase inhibition and cardiovascular risk | Charli E Harlow (+9) | 2022 | Human Molecular Genetics |
| 7548 | Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci | Samuel E. Jones (+26) | 2016 | PLOS Genetics |
| 7282 | Genome-Wide Association Study of Microscopic Colitis in the UK Biobank Confirms Immune-Related Pathogenesis | Harry D Green (+12) | 2019 | Journal of Crohn's and Colitis |
| 1863 | Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms | Samuel E. Jones (+31) | 2019 | Nature Communications |
| 5009 | Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes | Heming Wang (+44) | 2019 | Nature Communications |
| 8820 | Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates | Hassan S. Dashti (+31) | 2019 | Nature Communications |
| 7211 | Glycated haemoglobin measurements from UK Biobank are different to those in linked primary care records: implications for combining biochemistry data from research studies and routine clinical care | Katherine G Young (+2) | 2022 | International Journal of Epidemiology |
| 12761 | Guidance for estimating penetrance of monogenic disease-causing variants in population cohorts | Caroline F. Wright (+8) | 2024 | Nature Genetics |
| 8421 | Height, body mass index, and socioeconomic status: mendelian randomisation study in UK Biobank | Jessica Tyrrell (+13) | 2016 | The BMJ |
| 5138 | Higher adiposity and mental health: causal inference using Mendelian randomization | Francesco Casanova (+10) | 2021 | Human Molecular Genetics |
| 8967 | Hyperglycaemia is a causal risk factor for upper limb pathologies | Harry D Green (+14) | 2024 | International Journal of Epidemiology |
| 9501 | Identification and analysis of individuals who deviate from their genetically-predicted phenotype | Gareth Hawkes (+10) | 2023 | PLOS Genetics |
| 12248 | Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies | Charli E. Harlow (+32) | 2022 | American Journal of Human Genetics |
| 5186 | IgA Nephropathy Genetic Risk Score to Estimate the Prevalence of IgA Nephropathy in UK Biobank | Kittiya Sukcharoen (+11) | 2020 | Kidney International Reports |
| 9433 | Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records | Katherine S. Ruth (+11) | 2023 | BMC Medical Genomics |
| 5268 | Investigating causal relations between sleep traits and risk of breast cancer in women: mendelian randomisation study | Rebecca C Richmond (+17) | 2019 | The BMJ |
| 9739 | Investigating the role of platelets and platelet-derived transforming growth factor-β in idiopathic pulmonary fibrosis | Deborah L W Chong (+13) | 2023 | American Journal of Physiology - Lung Cellular and Molecular Physiology |
| 7500 | Mendelian randomization supports a causative effect of TSH on thyroid carcinoma | Jonathan M Fussey (+5) | 2020 | Endocrine Related Cancer |
| 10224 | Mendelian randomization to investigate the link between TSH and thyroid cancer | Jonathan M Fussey (+5) | 2021 | Endocrine Related Cancer |
| 2805 | Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry | Sara L Pulit (+22) | 2018 | Human Molecular Genetics |
| 8079 | Non-coding variants disrupting a tissue-specific regulatory element in HK1 cause congenital hyperinsulinism | Matthew N. Wakeling (+22) | 2022 | Nature Genetics |
| 13882 | PLIN1 Haploinsufficiency Causes a Favorable Metabolic Profile | Kashyap A Patel (+5) | 2022 | The Journal of Clinical Endocrinology & Metabolism |
| 8279 | Penetrance and expressivity of mitochondrial variants in a large clinically unselected population | Stuart J Cannon (+9) | 2023 | Human Molecular Genetics |
| 11585 | Penetrance of pathogenic genetic variants associated with premature ovarian insufficiency | Saleh Shekari (+18) | 2023 | Nature Medicine |
| 8346 | Proposed protocol for selection of living kidney donors with diabetes excludes >99% of people with diabetes | Mark Gilchrist (+1) | 2023 | Clinical Transplantation |
| 8505 | Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity | Valérie Turcot (+400) | 2017 | Nature Genetics |
| 12230 | Recurrent 17q12 microduplications contribute to renal disease but not diabetes | Stuart Cannon (+12) | 2022 | Journal of Medical Genetics |
| 10582 | Reduced penetrance of MODY-associated HNF1A/HNF4A variants but not GCK variants in clinically unselected cohorts | Uyenlinh L Mirshahi (+15) | 2022 | American Journal of Human Genetics |
| 12425 | Simulated distributions from negative experiments highlight the importance of the body mass index distribution in explaining depression-body mass index genetic risk score interactions | Francesco Casanova (+5) | 2022 | International Journal of Epidemiology |
| 9272 | Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis | Desana Kocevska (+72) | 2020 | Nature Human Behaviour |
| 7709 | The Common PKD1 p.(Ile3167Phe) Variant Is Hypomorphic and Associated with Very Early Onset, Biallelic Polycystic Kidney Disease | Miranda Durkie (+12) | 2023 | Human Mutation |
| 9702 | The Role of ONECUT1 Variants in Monogenic and Type 2 Diabetes Mellitus. | James Russ-Silsby (+10) | 2023 | Diabetes |
| 7362 | The impact of Mendelian sleep and circadian genetic variants in a population setting | Michael N. Weedon (+17) | 2022 | PLOS Genetics |
| 10714 | The impact of population-level HbA1c screening on reducing diabetes diagnostic delay in middle-aged adults: a UK Biobank analysis | Katherine G. Young (+7) | 2022 | Diabetologia |
| 14803 | Type 1 diabetes genetic risk score variation across ancestries using whole genome sequencing and array-based approaches | Ankit M. Arni (+6) | 2024 | Scientific Reports |
| 7474 | Unreliability of genotyping arrays for detecting very rare variants in human genetic studies: Example from a recent study of MC4R | Michael N Weedon (+3) | 2021 | Cell |
| 9742 | Using Mendelian Randomisation methods to understand whether diurnal preference is causally related to mental health | Jessica O'Loughlin (+14) | 2021 | Molecular Psychiatry |
| 13750 | Using genetics to understand the causal influence of higher BMI on depression | Jessica Tyrrell (+18) | 2018 | International Journal of Epidemiology |
| 5963 | Using human genetics to understand the disease impacts of testosterone in men and women | Katherine S Ruth (+21) | 2020 | Nature Medicine |
| 8422 | Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively | Andrew R. Wood (+11) | 2016 | Diabetologia |
| 13282 | Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height | Gareth Hawkes (+56) | 2024 | Nature Communications |
