| Application: | 7155, Epidemiology of mental health, cognitive function, pain and cardiometabolic disease. |
| Title: | Associations between active commuting and incident cardiovascular disease, cancer and mortality: prospective cohort study |
| Size: | 157639 B |
| Archived: | 5 Jul 2018 |
| Stability: | Complete |
| Personal: | No individual-level data |
Return 1480
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Notes
The aim of this study was to investigate the association between active commuting and incident cardiovascular disease (CVD), cancer, and all cause mortality. 263 450 participants (106?674 (52%) women; mean age 52.6), recruited from 22 sites across the UK. The exposure variable was the mode of transport used (walking, cycling, mixed mode v non-active (car or public transport)) to commute to and from work on a typical day. Cycle commuting was associated with a lower risk of CVD, cancer, and all cause mortality. Walking commuting was associated with a lower risk of CVD independent of major measured confounding factors. Initiatives to encourage and support active commuting could reduce risk of death and the burden of important chronic conditions.Application 7155
Epidemiology of mental health, cognitive function, pain and cardiometabolic disease.
Mental health problems place a large burden on the health service. As life expectancy increases, understanding cognitive decline is increasingly important. Identifying high risk groups enables us to detect problems early and target resources. Understanding the distribution of disease between groups can help elucidate the causes of disease and help identify new methods of prevention and treatment. Aim: To study the epidemiology of mental health, cognitive function, pain and cardiometabolic disease. Objectives: To examine the frequency, distribution, determinants and outcomes of these conditions, in relation to: demographics, lifestyle, comorbidity and medication UKB is representative of the general population in terms of age, sex and ethnicity but unrepresentative in terms of lifestyle. Therefore, it is not suitable to determine the overall prevalence of any condition but can, nonetheless, be used to compare the distribution of diseases between sub-groups and therefore determine associations between risk factors and disease frequency and outcome. This project builds on our ongoing study (774) which examines ethnic differences in cardiometabolic disease. We seek to extend the focus to examine other determinants of cardiometabolic disease as well as determinants of mood disorder, cognitive impairment and pain. We will compare participants with and without mood disorder, pain, cognitive impairment and cardiometabolic diease and participants with varying severity of these conditions in relation to a series of demographic and lifestyle factors in order to determine the factors associated with the conditions. We will also examine the association between these conditions and other diseases. The findings will help to identify individual at increased risk and modifiable factors that may help to prevent or alleviate these conditions. all participants
| Lead investigator: | Professor Jill Pell |
| Lead institution: | University of Glasgow |
15 related Returns
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|---|---|---|---|
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| 1682 | 7155 | PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study | 29 Jul 2019 |
| 1781 | 7155 | Red and processed meat consumption and breast cancer: UK Biobank cohort study and meta-analysis | 30 Sep 2019 |
| 2858 | 7155 | The association between driving time and unhealthy lifestyles: a cross-sectional, general population study of 386 493 UK Biobank participants | 24 Nov 2020 |
| 3675 | 7155 | Vitamin D and COVID-19 infection and mortality in UK Biobank | 27 Jul 2021 |
| 3674 | 7155 | Vitamin D concentrations and COVID-19 infection in UK Biobank | 27 Jul 2021 |
1 Publication
| Pub ID | Title | Author(s) | Year | Journal |
|---|---|---|---|---|
| 1481 | Association between active commuting and incident cardiovascular disease, cancer, and mortality: prospective cohort study | Carlos A Celis-Morales (+10) | 2017 | The BMJ |
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