: Category 17518

Category 17518
Blood biochemistry - Blood assays - Biological samples

Description

A range of key biochemistry markers were measured in the blood sample collected at recruitment (for all 500,000 participants) and at repeat assessment approx. 5 years later (for 20,000 participants). The biomarkers were selected for analysis because they represent established risk factors for disease, are established diagnostic measures, or characterised phenotypes not otherwise well assessed and are feasible to measure at scale.

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1 Sub-Category

Category ID	Description	Items
18518	Blood biochemistry processing	180+1

30 Data-Fields

Field ID	Description
30620	Alanine aminotransferase
30600	Albumin
30610	Alkaline phosphatase
30630	Apolipoprotein A
30640	Apolipoprotein B
30650	Aspartate aminotransferase
30710	C-reactive protein
30680	Calcium
30690	Cholesterol
30700	Creatinine
30720	Cystatin C
30660	Direct bilirubin
30730	Gamma glutamyltransferase
30740	Glucose
30750	Glycated haemoglobin (HbA1c)
30760	HDL cholesterol
30770	IGF-1
30780	LDL direct
30790	Lipoprotein A
30800	Oestradiol
30810	Phosphate
30820	Rheumatoid factor
30830	SHBG
30850	Testosterone
30840	Total bilirubin
30860	Total protein
30870	Triglycerides
30880	Urate
30670	Urea
30890	Vitamin D

1 Parent Category

Category ID	Description	Items
100080	Blood assays	+439

2 Resources

Preview	Name	Res ID
	Biochemistry assay quality procedures	5636
	Companion document for serum biomarker data	1227

13 Returns

Return ID	Description
2321	Lipoprotein A values that were outside the reportable range at assay
2167	Emmi Tikkanen et al (2018); Associations of Fitness, Physical Activity, Strength, and Genetic Risk With Cardiovascular Disease; Circulation (2018)
2166	Emmi Tikkanen et al; Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank; Scientific Reports (2008)
1602	N/A; Biomarker Assay Extended Dataset; N/A
2792	Zanetti et al; Birthweight, Type 2 Diabetes Mellitus, and Cardiovascular Disease: Addressing the Barker Hypothesis With Mendelian Randomization; Circulation: Genomic and Precision Medicine
2829	Tikkanen et al; Body composition and atrial fibrillation: a Mendelian randomization study; European Heart Journal 2019
2794	Fukaya et al; Clinical and Genetic Determinants of Varicose Veins; Circulation (2018)
3545	Horsfall et al.,; Genetically raised serum bilirubin levels and lung cancer: a cohort study and Mendelian randomisation using UK Biobank; Thorax (2020)
2163	Jonas B. Nielsen et al; Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development; AJHG (2018)
2793	Fall, Gustafsson, Orho-Melander, Ingelsson; Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank; Diabetologia (2018)
3522	Francis et al; Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci; PLOS Genetics (2021)
2831	Zanetti et al; Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion; Kidney International 2019
2888	Zanetti et al; Urinary Albumin, Sodium, and Potassium and Cardiovascular Outcomes in the UK Biobank; Hypertension (2020)