Biological samples ⏵ Blood assays ⏵ NMR metabolomics
Description
NMR metabolic biomarkers generated by Nightingale Health. Data was released as 3 phases, measuring 251 metabolic biomarkers for EDTA plasma samples from approx 491,000 UK Biobank participants.Metabolic biomarkers were measured from randomly selected EDTA plasma samples (aliquot 3) using a high-throughput NMR-based metabolic biomarker profiling platform developed by Nightingale Health Ltd. The measurements took place between June 2019 and April 2020 (Phase 1), April 2020 and June 2022 (Phase 2) and September 2022 and November 2023 (Phase 3) using 9 spectrometers at Nightingale Health, based in Finland.
The biomarkers span multiple metabolic pathways, including lipoprotein lipids in 14 subclasses, fatty acids and fatty acid compositions, as well as various low-molecular weight metabolites, such as amino acids, ketone bodies, and glycolysis metabolites quantified in molar concentration units.
Previously available data from Phase 1 of the study has been updated as a part of the July 2023 release due to updates in spectrometer recalibration (further information can be found in Resource 130).
